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PICAMILONE Picamilone, also spelled Picamilon, Pikamilon,
Pycamilon (with or without an
e on the
end), is a Russian developed nootropic. Picamilone is Niacin (vitamin
B3) bonded to GABA but its effects are much greater and broader than just taking
GABA and Niacin. Picamilone rapidly crosses the blood-brain barrier and increases the rate of intracranial and cortex blood circulation. It has been cited as a better vasodilator than either Hydergine or Vinpocetine. The combination acts as a mild stimulant, yet depresses aggression. This could be the clear actions of Niacin and GABA (after all diazepam's such as valium increase or enhance the activity of GABA). But, Picamilone has a tranquilizing effect, without a sedative effect but actually with an element of stimulatory action. Other Russian studies with Picamilone show it to improve patients with a mild to moderate memory impairment, emotional, hearing and speech difficulties. Furthermore, Picamilone has reduced migraine or headache pain and aided in alcohol withdraw. One study showed an improvement for patients suffering from an eye disorder called pigmented retinal abiotrophy (PRA) after 10-days. Most improvements are noted quickly, often within a week of continuous treatment and studies show that Picamilone has very low toxicity, with few side effects. |
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