Moclobemide in long-term treatment.

Stefanis CN, Merz-Frei K
Department of Psychiatry,
University of Athens, Eginition Hospital, Greece.
Acta Psychiatr Scand Suppl 1990;360:67-8 

ABSTRACT

Patients requiring long-term treatment of depression (at least 60 days) were followed up at monthly intervals under treatment with moclobemide. A total of 102 patients completed 1 year of treatment; the mean dose at the start of treatment was 340 mg daily, decreasing to 300 mg after a year. Three quarters of these patients were suffering from endogenous depression. The investigator's overall assessment of efficacy was good or very good for 96% of patients; efficacy judged together with tolerance was good or very good for 85% of patients. There were no noteworthy changes in safety parameters throughout the study, and adverse events were mainly minor and of short duration. The result of this analysis suggests that moclobemide is effective, safe and well tolerated in long-term administration. 

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                            Moclobemide research

         1.    Moclobemide  for the treatment of depression
         2.    Moclobemide  in clinical psychopharmacology
         3.    Moclobemide  therapy for chronic depressive disorders 
         4.    Moclobemide  and tranylcypromine in depression
         5.    Moclobemide  and fluoxetine for panic disorder
         6.    Moclobemide  in patients with dementia and depression
         7.    Moclobemide  in mild major depression
         8.    Moclobemide  for depression
         9.    Moclobemide  in treatment of major depressive episodes
        10.   Moclobemide  vs. placebo in the treatment of depression
        11.   Moclobemide  long-term treatment in major depression
        12.   Moclobemide  and sertraline in the treatment of depression
        13.   Moclobemide  in long-term treatment
        14.   Moclobemide  vs fluoxetine for double depression
        15.   Moclobemide  vs fluoxetine in major depressive disorders
        16.   Moclobemide  vs fluoxetine in major depression

 

 

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