Huperzine A

Huperzine is a unique nutritional supplement that offers hope to those suffering from Alzheimer's disease and other age-related mental conditions. Alzheimer's is characterized by the destruction of nerve cells in several key areas of the brain devoted to mental functions, including a substantial loss of presynaptic cholinergic neurons in brains of patients.

This results in a dramatic decrease in the neurotransmitter acetylcholine, a vital neurotransmitter with a fundamental role in memory and intracellular communication between nerve cells. Research has shown that levels of acetylcholine are deficient in the brains of patients with Alzheimer's disease. What little acetylcholine is still produced in the patient's brain is quickly broken down by the brain enzyme, acetylcholinesterase (AChE), leading to a shortage of the neurotransmitter, contributing to the patient's loss of memory and other cognitive functions.

Huperzine is derived from the ancient Chinese herb Huperzia serrata, traditionally used to treat fever, inflammation and irregular menstruation. In the late 1980s, researchers discovered that Huperzine-A, an alkaloid extracted from the raw plant, readily crosses the blood-brain barrier to prevent acetylcholinesterase (AChE) from destroying acetylcholine. Researchers found that Huperzine works in a manner similar to the AChE inhibitors (such as tacrine and donepezil) to impair the ability of AChE to degrade acetylcholine.  By inhibiting the actions of AChE and increasing acetylcholine concentrations in the brain, Huperzine-A has been shown to be effective in alleviating some of the symptoms associated with acetylcholine deficiencies.

"Hup-A appears to bind more tightly and specifically to acetylcholinesterase than the other AChE inhibitors," crystallographer Prof. Joel Sussman, one of the authors of the study said. "It is as if this natural substance were ingeniously designed to fit into the exact spot in AChE where it will do the most good."

Researchers have demonstrated that patients suffering from Alzheimer's and various other memory disorders gain significant benefit from huperzine, both in terms of memory and life quality. In one placebo-controlled, double-blinded study, researchers found that 58% of Alzheimer's patients experience significant improvement in both cognitive and memory function when given 200 mcg of Huperzine per day. Other significant effects have been noted in patients, both in terms of their life quality and their ability to retrieve past memories. Huperzine's memory-enhancing properties suggest that it may be an effective agent for improving memory and learning in healthy humans as well. These findings suggest that Huperzine not only protects from the effects of Alzheimer's and senile memory deficits, but also provides a unique and exciting supplement for supporting memory in the healthy aging human as well.



Order  Acetyl L-Carnitine 500 mg 60 caps $9.99
Order  Alpha GPC + Huperzine A 300 mg 60 caps $12.99
Order  Aniracetam 750 mg 30 caps $19.99
Order  CDP Choline + Huperzine A 200 mg 60 caps $19.99
Order  Centrophenoxine + Huperzine A 250 mg 60 caps $19.99
Order  Galantamine 8 mg 60 caps $39.99
Order  Idebenone                12 @ $15 = $180 45 mg 60 caps $23.99
Order  Phosphatidylserine      6 bottles @ $18 100 mg 60 caps $29.99
Order  Oxiracetam 750 mg 30 caps $23.99
Order  Piracetam 800 mg 60 caps $14.99
Order  Pyritinol  200 mg 60 caps $12.99
Order  Vinpocetine 10 mg 60 caps $9.99
Order  Get SmartTM     as reported in Wired magazine  click to read 789 mg 60 caps $55.99

Get Smart
  brain formula
        ingredients in 2 capsules
Aniracetam 766 mg    more potent analog of piracetam
Centrophenoxine 390 mg    raises brain acetylcholine levels
CDP Choline 200 mg    raises brain acetylcholine levels
Gastrodin 140 mg    regenerates brain function - increases brain blood flow
Oxiracetam 40 mg   promotes communication between the 2 brain hemispheres
Vinpocetine 8 mg   increases circulation to the brain
Galantamine 320 mcg   prolongs life of acetylcholine in the brain
Huperzine A 200 mcg   prolongs life of acetylcholine in the brain


"We took my son off Paxil and put him on Get
Smart and his grades improved.
My other son's grades went from B's to A's since starting on Get

"I noticed the effect from Get Smart almost immediately. My memory was better. I pay better attention to detail."

   more Testimonials  click

Autisim feedback on Get Smart (from

"Our son's articulation improved within 24 hours after starting Get Smart."
the boys have made some great academic and language gains."